Synthesis and in vitro cytotoxic activity of compounds with pro-apoptotic potential.

نویسندگان

  • Gisell Apicela Soares
  • Renata Barbosa de Oliveira
  • Saulo Fernandes de Andrade
  • Ricardo José Alves
  • Carlos Leomar Zani
  • Elaine Maria de Souza-Fagundes
چکیده

In our search for new anticancer therapies, some compounds synthesized in our lab were selected and their potential cytotoxic activity was evaluated in vitro against two cancer cells lines including a solid tumor (UACC-62, melanoma) and a human lymphoma (JURKAT). Compounds showing cytotoxic activity were subjected to an apoptosis assay. Two compounds showed promising results.

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عنوان ژورنال:
  • Molecules

دوره 15 1  شماره 

صفحات  -

تاریخ انتشار 2009